The authors followed Guidelines developed by the Neurotraumatology Committee of the World Federation of Neurosurgical Societies for the management of mild brain injury presenting at emergency departments. The abstract below is taken from the Journal of Neurology Neurosurgery and Psychiatry March 2004 issue.
Prospective validation of a proposal for diagnosis and management of patients attending the emergency department for mild head injury
J. Neurol. Neurosurg. Psychiatry, Mar 2004; 75: 410 - 416.
A Fabbri1, F Servadei2, G Marchesini3, A M Morselli-Labate3, M Dente1, T Iervese1, M Spada1 and A Vandelli1
1 Dipartimento Emergenza-Urgenza Accettazione, Ospedale GB Morgagni, Azienda Unit¢ Sanitaria Locale di Forl↓, Italy 2 Divisione di Neurochirurgia per la Traumatologia, Ospedale M. Bufalini, Azienda Unit¢ Sanitaria Locale di Cesena, Italy 3 Dipartimento di Medicina Interna e Gastroenterologia, Universit¢ degli Studi di Bologna, Italy
Correspondence to: Dr A Fabbri Dipartimento Emergenza-Urgenza Accettazione, Ospedale GB Morgagni, Azienda USL di Forl↓, 1 P.le Solieri-I-47100 Forl↓, Italy; andfabbri@libero.it
Background: In mild head injury, predictors to select patientsfor computed tomography (CT) and/or to plan proper managementare needed. The strength of evidence of published recommendationsis insufficient for current use. We assessed the diagnosticaccuracy and the clinical validity of the proposal of the NeurotraumatologyCommittee of the World Federation of Neurosurgical Societieson mild head injury from an emergency department perspective.
Methods: In a three year period, 5578 adolescent and adult subjectswere prospectively recruited and managed according to the proposedprotocol. Outcome measures were: (a) any post-traumatic lesion;(b) need for neurosurgical intervention; (c) unfavourable outcome(death, permanent vegetative state or severe disability) aftersix months. The predictive value of a model based on five variables(Glasgow coma score, clinical findings, risk factors, neurologicaldeficits, and skull fracture) was tested by logistic regressionanalysis.
Findings: At first CT evaluation 327 patients (5.9%) had intracranialpost-traumatic lesions. In 16 cases (0.3%) previously undiagnosedlesions were detected after re-evaluation within seven days.Neurosurgical intervention was needed in 71 patients (1.3%)and an unfavourable outcome occurred in 39 cases (0.7%). Thearea under the ROC curve of the variables in predicting post-traumaticlesions was 0.906 (0.009) (sensitivity 70.0%, specificity 94.1%at best cut off), neurosurgical intervention was 0.926 (0.016)(sensitivity 81.7%, specificity 94.1%), and unfavourable outcomewas 0.953 (0.014) (sensitivity 88.1%, specificity 95.1%).
Interpretation: The variables prove highly accurate in the predictionof clinically meaningful outcomes, when applied to a consecutiveset of patients with mild head injury in the clinical settingof a 1st level emergency department.